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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS6
All Species:
24.55
Human Site:
S726
Identified Species:
54
UniProt:
Q9UKP5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKP5
NP_922932.2
1117
125273
S726
I
E
G
F
F
N
D
S
L
P
R
G
G
Y
M
Chimpanzee
Pan troglodytes
XP_526907
1117
125238
S726
I
E
G
F
F
N
D
S
L
P
R
G
G
Y
M
Rhesus Macaque
Macaca mulatta
XP_001084793
1117
125301
S726
I
E
G
F
F
N
D
S
L
P
R
G
G
Y
M
Dog
Lupus familis
XP_535255
1117
125043
S726
I
E
G
F
F
N
D
S
L
P
R
G
G
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
P58459
1104
121067
A715
I
E
G
V
F
S
P
A
L
P
G
T
G
Y
E
Rat
Rattus norvegicus
Q1EHB3
1595
175796
Y1047
V
D
D
F
Y
Y
D
Y
N
F
I
N
F
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513889
903
100601
T522
S
K
S
N
R
C
V
T
N
S
I
P
A
A
E
Chicken
Gallus gallus
XP_424749
1118
125075
S727
I
E
G
F
F
N
D
S
L
P
R
G
G
Y
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923204
1116
124633
S725
T
E
G
L
F
N
D
S
L
P
R
G
G
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
Q763
V
K
G
T
F
N
E
Q
G
T
F
G
Y
N
E
Sea Urchin
Strong. purpuratus
XP_001180742
1320
148448
E190
V
G
G
T
F
N
G
E
L
V
A
G
D
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.6
98.4
N.A.
59.7
30.4
N.A.
72.9
92.4
N.A.
82.8
N.A.
N.A.
N.A.
21.4
39.7
Protein Similarity:
100
99.9
99.7
98.9
N.A.
74.4
41.5
N.A.
75.7
95.8
N.A.
90.1
N.A.
N.A.
N.A.
31.1
54.6
P-Site Identity:
100
100
100
100
N.A.
53.3
13.3
N.A.
0
100
N.A.
86.6
N.A.
N.A.
N.A.
26.6
40
P-Site Similarity:
100
100
100
100
N.A.
66.6
40
N.A.
13.3
100
N.A.
86.6
N.A.
N.A.
N.A.
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
64
0
0
0
0
0
10
0
0
% D
% Glu:
0
64
0
0
0
0
10
10
0
0
0
0
0
0
37
% E
% Phe:
0
0
0
55
82
0
0
0
0
10
10
0
10
0
0
% F
% Gly:
0
10
82
0
0
0
10
0
10
0
10
73
64
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
55
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% I
% Lys:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
73
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% M
% Asn:
0
0
0
10
0
73
0
0
19
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
64
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
55
0
0
0
0
% R
% Ser:
10
0
10
0
0
10
0
55
0
10
0
0
0
0
0
% S
% Thr:
10
0
0
19
0
0
0
10
0
10
0
10
0
0
0
% T
% Val:
28
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
0
10
0
0
0
0
10
73
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _